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Will Rodman (James Franco) is a San Francisco scientist who has been trying to develop a cure for Alzheimer's disease by testing a genetically engineered retrovirus on chimpanzees. The virus mutates the chimpanzees, giving them a human level of intelligence. One of his test subjects, a female chimpanzee, goes on a rampage because she believes her baby, to whom she secretly gave birth, is threatened. She is killed after disrupting a board meeting. Will's boss Steven Jacobs (David Oyelowo) orders subordinate Robert Franklin (Tyler Labine) to put all the test chimpanzees down, but he cannot bring himself to kill the chimpanzee's baby, and instead gives him to Will, who names him Caesar (Andy Serkis) and raises him in his house. Caesar has inherited his mother's high intelligence, and learns quickly.
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